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分子生物学
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查看说明书STAT6 Rabbit pAb
Cat#:DPA01407应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | Phospho-STAT6 (Tyr641) Rabbit pAb |
| Cat No.: | DPA05421 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,FC,IP |
| Recommended Dilution: | WB: 1:1000 FC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr641 of human STAT6 |
| Calculated Molecular Weight: | 94 kDa |
| Observed Molecular Weight: | 110 kDa |
| GenBank Accession Number: | P42226 |
| Gene ID (NCBI): | 6778 |
| Synonyms: | STAT6B; STAT6C; D12S1644; IL-4-STAT |
| Background: | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| Category: | Primary Ab |
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