蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书| Product Name: | Recombinant Rat IL1R2 / IL1RB / CD121b Protein (His tag) |
| Cat No.: | TP06423 |
| TargetID: | P43303 |
| Source: | HEK293 Cells |
| Gene Accession Number: | 117022 |
| Peptide Sequence: | Met 1-Glu 355 |
| Tag: | C-His |
| Purity: | >95% as determined by SDS-PAGE. |
| Formulation: | Freeze-dried powder |
| Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
| Category: | Protein |
| Species Reactivity: | Rat |
| Predicted Molecular Mass: | 39.7 kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | IL1R2 |
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