| Product Name: | Recombinant Mouse CD146 / MCAM Protein (His tag) |
| Cat No.: | TP08571 |
| TargetID: | Q8R2Y2 |
| Source: | HEK293 Cells |
| Gene Accession Number: | 84004 |
| Peptide Sequence: | Met 1-Val 563 |
| Tag: | C-His |
| Purity: | >95% as determined by SDS-PAGE. |
| Formulation: | Freeze-dried powder |
| Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
| Category: | Protein |
| Species Reactivity: | Mouse |
| Predicted Molecular Mass: | 61.3 kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration (By similarity). |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | 1-gicerin;AV025631;CD146;CD149;Muc18;s-endo;s-gicerin |
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