蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书| Product Name: | Recombinant Human 5-Hydroxytryptamine Receptor 1A (HTR1A) Protein |
| Cat No.: | TP08902-1 |
| TargetID: | P08908 |
| Source: | E.coli |
| Gene Accession Number: | 3350 |
| Peptide Sequence: | Glu179~Gln422 |
| Tag: | N-6His |
| Purity: | > 90% |
| Formulation: | PBS, pH7.4 containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
| Storage Buffer: | PBS, pH7.4, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
| Storage Condition: | Aliquot and store at -20¡ãC to -80¡ãC for up to 6 months, buffer containing 7686% glycerol is recomm |
| Category: | Protein |
| Species Reactivity: | Human |
| Predicted Molecular Mass: | 24kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli. |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | 5HTR1A; 5HTR1-A; 5-HTR1-A; ADRB2RL1; ADRBRL1; Serotonin Receptor 1A |
相关产品
