| Product Name: | Recombinant Pig Interleukin 6 (IL6) protein |
| Cat No.: | TP08636 |
| TargetID: | P26893 |
| Source: | E.coli |
| Gene Accession Number: | 100628202 |
| Peptide Sequence: | Glu30~Met212 |
| Tag: | N-6His |
| Purity: | > 95% |
| Formulation: | PBS |
| Storage Buffer: | PBS |
| Storage Condition: | Aliquot and store at -20¡ãC to -80¡ãC for up to 6 months, buffer containing 7686% glycerol is recomm |
| Category: | Protein |
| Species Reactivity: | Pig |
| Predicted Molecular Mass: | 24.0kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells. |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | MGI2-A; MGI2A; HGF; BSF2; HSF; IFNB2; B-Cell Stimulatory Factor-2; Hybridoma/Plasmacytoma Growth Fac |
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