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Dystrophin Rabbit pAb

Cat No.: DPA01435
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Product Name: Dystrophin Rabbit pAb
Cat No.: DPA01435
Clonality: Polyclonal
Species Reactivity: Mouse, Rat
Tested Applications: WB
Recommended Dilution: WB: 1:1000
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of mouse Dystrophin
Calculated Molecular Weight: 426 kDa
GenBank Accession Number: P11530
Gene ID (NCBI): 13405
Synonyms: dys; mdx; pke; Dp71; Dp427; DXSmh7; DXSmh9
Background: This gene encodes a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers in skeletal and cardiac muscles. The encoded protein, dystrophin, is part of the dystrophin-glycoprotein complex, which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. This protein is required for proper development and organization of myofibers as contractile units in striated muscles. Mutations in the human gene cause Duchenne and Becker Muscular Dystrophies and a form of heart disease called DMD-associated dilated cardiomyopathy. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2015]
Category: Primary Ab
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