Eukaryotic Programmed Cell Death Protein 1 (PD1)
Cat#:TP05060应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | PD1 Rabbit pAb |
Cat No.: | DPA01546 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,FC,IP |
Recommended Dilution: | WB: 1:1000 IHC: 1:20 FC: 1:50 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human PD1 |
Calculated Molecular Weight: | 32 kDa |
Observed Molecular Weight: | 52-65 kDa |
GenBank Accession Number: | Q15116 |
Gene ID (NCBI): | 5133 |
Synonyms: | PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1 |
Background: | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |