Product Name: | PADI3/PAD3 Rabbit pAb |
Cat No.: | DPA01855 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IP |
Recommended Dilution: | WB: 1:1000 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human PADI3/PAD3 |
Calculated Molecular Weight: | 75 kDa |
Observed Molecular Weight: | 75 kDa |
GenBank Accession Number: | Q9ULW8 |
Gene ID (NCBI): | 51702 |
Synonyms: | PAD3; PDI3; UHS1 |
Background: | This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |
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