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Prostate Specific Antigen Rabbit pAb

Cat No.: DPA01960
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Product Name: Prostate Specific Antigen Rabbit pAb
Cat No.: DPA01960
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC
Recommended Dilution: WB: 1:2000-1:10000
IHC: 1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Prostate Specific Antigen
Calculated Molecular Weight: 29 kDa
Observed Molecular Weight: 29 kDa
GenBank Accession Number: P07288
Gene ID (NCBI): 354
Synonyms: APS; PSA; hK3; KLK2A1
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]
Category: Primary Ab
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