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Munc 13-4 Rabbit pAb

Cat No.: DPA02077
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Product Name: Munc 13-4 Rabbit pAb
Cat No.: DPA02077
Clonality: Polyclonal
Species Reactivity: Human, Mouse
Tested Applications: WB,ICC/IF,FC
Recommended Dilution: WB: 1:1000
ICC/IF: 1:50
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Munc 13-4
Calculated Molecular Weight: 123 kDa
Observed Molecular Weight: 123 kDa
GenBank Accession Number: Q70J99
Gene ID (NCBI): 201294
Synonyms: FHL3; HLH3; HPLH3; Munc13-4
Background: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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