| Product Name: | Munc 13-4 Rabbit pAb |
| Cat No.: | DPA02077 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Munc 13-4 |
| Calculated Molecular Weight: | 123 kDa |
| Observed Molecular Weight: | 123 kDa |
| GenBank Accession Number: | Q70J99 |
| Gene ID (NCBI): | 201294 |
| Synonyms: | FHL3; HLH3; HPLH3; Munc13-4 |
| Background: | This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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