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LOX 1 Rabbit pAb

Cat No.: DPA02517
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Product Name: LOX 1 Rabbit pAb
Cat No.: DPA02517
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Recommended Dilution: WB: 1:1000
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human LOX 1
Calculated Molecular Weight: 31 kDa
Observed Molecular Weight: 50 kDa
GenBank Accession Number: P78380
Gene ID (NCBI): 4973
Synonyms: LOX1; LOXIN; SLOX1; CLEC8A; SCARE1
Background: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Category: Primary Ab
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