| Product Name: | TNF alpha Rabbit pAb | 
| Cat No.: | DPA02790 | 
| Clonality: | Polyclonal | 
| Species Reactivity: | Human, Mouse | 
| Tested Applications: | WB,FC,IP | 
| Recommended Dilution: | WB: 1:1000 FC: 1:100 IP: 1:20  | 
							
| Size: | 30ul 50ul 100uL | 
| Format: | Liquid | 
| Source: | Rabbit | 
| Purification Method: | Affinity Purification | 
| Isotype: | IgG | 
| Conjugate: | Un-conjugated | 
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a | 
| Immunogen: | Recombinant protein of human TNF alpha | 
| Calculated Molecular Weight: | 26 kDa | 
| Observed Molecular Weight: | 26 kDa | 
| GenBank Accession Number: | P01375 | 
| Gene ID (NCBI): | 7124 | 
| Synonyms: | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha | 
| Background: | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008] | 
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