Recombinant Human KLK7 Protein
Cat#:TP02751应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Kallikrein 7 Rabbit pAb |
Cat No.: | DPA02824 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000 IHC: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human Kallikrein 7 |
Calculated Molecular Weight: | 28 kDa |
Observed Molecular Weight: | 28 kDa |
GenBank Accession Number: | P49862 |
Gene ID (NCBI): | 5650 |
Synonyms: | hK7; SCCE; PRSS6 |
Background: | This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011] |
Category: | Primary Ab |