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CHD3 Rabbit pAb

Cat No.: DPA03189
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Product Name: CHD3 Rabbit pAb
Cat No.: DPA03189
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC
Recommended Dilution: WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human CHD3
Calculated Molecular Weight: 227 kDa
Observed Molecular Weight: 260 kDa
GenBank Accession Number: Q12873
Gene ID (NCBI): 1107
Synonyms: ZFH; Mi-2a; Mi2-ALPHA
Background: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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