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TMEM119 Rabbit pAb

Cat No.: DPA03510
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Product Name: TMEM119 Rabbit pAb
Cat No.: DPA03510
Clonality: Polyclonal
Species Reactivity: Mouse
Tested Applications: IHC
Recommended Dilution: IHC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of mouse TMEM119
Calculated Molecular Weight: 29 kDa
GenBank Accession Number: Q8R138
Gene ID (NCBI): 231633
Synonyms: obif; AW208946; BC025600
Background: Plays an important role in bone formation and normal bone mineralization (PubMed:26207632, PubMed:22416756, PubMed:20025746). Promotes the differentiation of myoblasts into osteoblasts (PubMed:22416756, PubMed:20025746, PubMed:22579779). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway (PubMed:21239498, PubMed:22579779). Upregulates the expression of ATF4 which plays a central role in osteoblast differentiation (PubMed:24362451). Essential for normal spermatogenesis and late testicular differentiation (PubMed:26207632).
Category: Primary Ab
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