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Integrin beta 4 Rabbit pAb

Cat No.: DPA03701
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Product Name: Integrin beta 4 Rabbit pAb
Cat No.: DPA03701
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF
Recommended Dilution: WB: 1:1000-1:5000
ICC/IF: 1:50-1:200
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Integrin beta 4
Calculated Molecular Weight: 202 kDa
Observed Molecular Weight: 202 kDa
GenBank Accession Number: P16144
Gene ID (NCBI): 3691
Synonyms: CD104; GP150
Background: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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