蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书| Product Name: | T-bet/Tbx21 Rabbit pAb |
| Cat No.: | DPA04030 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | IHC |
| Recommended Dilution: | IHC: 1:200 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human T-bet/Tbx21 |
| Calculated Molecular Weight: | 58 kDa |
| GenBank Accession Number: | Q9UL17 |
| Gene ID (NCBI): | 30009 |
| Synonyms: | TBET; T-PET; T-bet; TBLYM |
| Background: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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