| Product Name: | SCRIBBLE Rabbit pAb |
| Cat No.: | DPA04350 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF |
| Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human SCRIBBLE |
| Calculated Molecular Weight: | 175 kDa |
| Observed Molecular Weight: | 240 kDa |
| GenBank Accession Number: | Q14160 |
| Gene ID (NCBI): | 23513 |
| Synonyms: | CRIB1; SCRB1; SCRIB1; Vartul |
| Background: | This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
| Category: | Primary Ab |
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