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SUN2 Rabbit pAb

Cat No.: DPA04384
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Product Name: SUN2 Rabbit pAb
Cat No.: DPA04384
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC
Recommended Dilution: WB: 1:2000
IHC: 1:50
ICC/IF: 1:100
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human SUN2
Calculated Molecular Weight: 80 kDa
Observed Molecular Weight: 80 kDa
GenBank Accession Number: Q9UH99
Gene ID (NCBI): 25777
Synonyms: UNC84B
Background: SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
Category: Primary Ab
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