| Product Name: | eIF3e Rabbit pAb |
| Cat No.: | DPA04672 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human eIF3e |
| Calculated Molecular Weight: | 52 kDa |
| Observed Molecular Weight: | 52 kDa |
| GenBank Accession Number: | P60228 |
| Gene ID (NCBI): | 3646 |
| Synonyms: | INT6; EIF3S6; EIF3-P48; eIF3-p46 |
| Background: | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. |
| Category: | Primary Ab |
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