| Product Name: | GRAF Rabbit pAb |
| Cat No.: | DPA04719 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,FC |
| Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 FC: 1:20-1:100 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human GRAF |
| Calculated Molecular Weight: | 92 kDa |
| Observed Molecular Weight: | 92 kDa |
| GenBank Accession Number: | Q9UNA1 |
| Gene ID (NCBI): | 23092 |
| Synonyms: | GRAF; GRAF1; OPHN1L; OPHN1L1 |
| Background: | Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017] |
| Category: | Primary Ab |
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