蛋白
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检测试剂盒
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分子生物学
规格：
查看说明书PHOX2A Rabbit pAb
Cat#:DPA04713应用：WB,IP
| Product Name: | PHOX2A Rabbit pAb |
| Cat No.: | DPA04723 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human PHOX2A |
| Calculated Molecular Weight: | 30 kDa |
| Observed Molecular Weight: | 30 kDa |
| GenBank Accession Number: | O14813 |
| Gene ID (NCBI): | 401 |
| Synonyms: | ARIX; FEOM2; NCAM2; PMX2A; CFEOM2 |
| Background: | The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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