Recombinant Huntingtin Interacting Protein 2 (HIP2)
Cat#:TP04389应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | HIP2 Rabbit pAb |
Cat No.: | DPA04734 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,IP |
Recommended Dilution: | WB: 1:2000 IHC: 1:50-1:200 ICC/IF: 1:50 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human HIP2 |
Calculated Molecular Weight: | 22 kDa |
Observed Molecular Weight: | 22 kDa |
GenBank Accession Number: | P61086 |
Gene ID (NCBI): | 3093 |
Synonyms: | LIG; HIP2; HYPG; UBC1; E2-25K |
Background: | The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |