蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Wilms Tumor Protein Rabbit pAb
Cat#:DPA04834应用：WB,IHC,ICC/IF,FC
| Product Name: | Wilms Tumor Protein Rabbit pAb |
| Cat No.: | DPA04834 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Wilms Tumor Protein |
| Calculated Molecular Weight: | 49 kDa |
| Observed Molecular Weight: | 51-60 kDa |
| GenBank Accession Number: | P19544 |
| Gene ID (NCBI): | 7490 |
| Synonyms: | GUD; AWT1; WAGR; WT33; NPHS4; WIT-2; EWS-WT1 |
| Background: | This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015] |
| Category: | Primary Ab |
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