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HLA-DR Rabbit pAb

Cat No.: DPA04910
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Product Name: HLA-DR Rabbit pAb
Cat No.: DPA04910
Clonality: Polyclonal
Species Reactivity: Human, Rat
Tested Applications: WB,IHC,ICC/IF,FC
Recommended Dilution: WB: 1:2000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human HLA-DR
Calculated Molecular Weight: 29 kDa
Observed Molecular Weight: 29 kDa
GenBank Accession Number: P01903
Gene ID (NCBI): 3122
Synonyms: HLA-DRA1
Background: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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