蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书SDHB Rabbit pAb
Cat#:DPA04921应用：WB,IHC,FC,IP
| Product Name: | SDHB Rabbit pAb |
| Cat No.: | DPA04921 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,FC,IP |
| Recommended Dilution: | WB: 1:2000 IHC: 1:50 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human SDHB |
| Calculated Molecular Weight: | 32 kDa |
| Observed Molecular Weight: | 32 kDa |
| GenBank Accession Number: | P21912 |
| Gene ID (NCBI): | 6390 |
| Synonyms: | IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP |
| Background: | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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