产品中心

Langerin Rabbit pAb

Cat No.: DPA04926
规格:
查看说明书
Product Name: Langerin Rabbit pAb
Cat No.: DPA04926
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: IHC
Recommended Dilution: IHC: 1:200
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human Langerin
Calculated Molecular Weight: 37 kDa
GenBank Accession Number: Q9UJ71
Gene ID (NCBI): 50489
Synonyms: CLEC4K
Background: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010]
Category: Primary Ab
武汉天正源生物科技有限公司 版权所有 | 鄂ICP备2023000437号-1