Recombinant Human CD207 Protein
Cat#:TP01489应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Langerin Rabbit pAb |
Cat No.: | DPA04926 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | IHC |
Recommended Dilution: | IHC: 1:200 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human Langerin |
Calculated Molecular Weight: | 37 kDa |
GenBank Accession Number: | Q9UJ71 |
Gene ID (NCBI): | 50489 |
Synonyms: | CLEC4K |
Background: | The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010] |
Category: | Primary Ab |