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CD163 Rabbit pAb

Cat No.: DPA04945
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Product Name: CD163 Rabbit pAb
Cat No.: DPA04945
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,IP
Recommended Dilution: WB: 1:1000-1:5000
IHC: 1:50-1:200
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human CD163
Calculated Molecular Weight: 126 kDa
Observed Molecular Weight: 150 kDa
GenBank Accession Number: Q86VB7
Gene ID (NCBI): 9332
Synonyms: M130; MM130; SCARI1
Background: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Category: Primary Ab
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