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Collagen XVII Rabbit pAb

Cat No.: DPA04958
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Product Name: Collagen XVII Rabbit pAb
Cat No.: DPA04958
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,IP
Recommended Dilution: WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Collagen XVII
Calculated Molecular Weight: 150 kDa
Observed Molecular Weight: 180,130 kDa
GenBank Accession Number: Q9UMD9
Gene ID (NCBI): 1308
Synonyms: ERED; BP180; BPA-2; BPAG2; LAD-1; BA16H23.2
Background: This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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