产品中心

PRMT6 Rabbit pAb

Cat No.: DPA04979
规格:
查看说明书
Product Name: PRMT6 Rabbit pAb
Cat No.: DPA04979
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Recommended Dilution: WB: 1:1000
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human PRMT6
Calculated Molecular Weight: 42 kDa
Observed Molecular Weight: 42 kDa
GenBank Accession Number: Q96LA8
Gene ID (NCBI): 55170
Synonyms: HRMT1L6
Background: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
Category: Primary Ab
武汉天正源生物科技有限公司 版权所有 | 鄂ICP备2023000437号-1