MYBPC3 Rabbit pAb
Cat#:DPA01889应用:WB
Product Name: | MYBPC3 Rabbit pAb |
Cat No.: | DPA05008 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000-1:5000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human MYBPC3 |
Calculated Molecular Weight: | 141 kDa |
Observed Molecular Weight: | 150 kDa |
GenBank Accession Number: | Q14896 |
Gene ID (NCBI): | 4607 |
Synonyms: | FHC; CMH4; CMD1MM; LVNC10; MYBP-C |
Background: | MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |