HuR/ELAVL1 Rabbit pAb
Cat#:DPA05013应用:WB,IHC,ICC/IF,FC,IP
Product Name: | HuR/ELAVL1 Rabbit pAb |
Cat No.: | DPA05013 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:1000 IHC: 1:100 ICC/IF: 1:50 FC: 1:20-1:100 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human HuR/ELAVL1 |
Calculated Molecular Weight: | 36 kDa |
Observed Molecular Weight: | 36 kDa |
GenBank Accession Number: | Q15717 |
Gene ID (NCBI): | 1994 |
Synonyms: | HUR; Hua; MelG; ELAV1 |
Background: | The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012] |
Category: | Primary Ab |