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HuR/ELAVL1 Rabbit pAb

Cat No.: DPA05013
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Product Name: HuR/ELAVL1 Rabbit pAb
Cat No.: DPA05013
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:100
ICC/IF: 1:50
FC: 1:20-1:100
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human HuR/ELAVL1
Calculated Molecular Weight: 36 kDa
Observed Molecular Weight: 36 kDa
GenBank Accession Number: Q15717
Gene ID (NCBI): 1994
Synonyms: HUR; Hua; MelG; ELAV1
Background: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
Category: Primary Ab
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