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MYSM1 Rabbit pAb

Cat No.: DPA05015
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Product Name: MYSM1 Rabbit pAb
Cat No.: DPA05015
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IP
Recommended Dilution: WB: 1:1000
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human MYSM1
Calculated Molecular Weight: 95 kDa
Observed Molecular Weight: 96,55 kDa
GenBank Accession Number: Q5VVJ2
Gene ID (NCBI): 114803
Synonyms: 2ADUB; 2A-DUB
Background: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Category: Primary Ab
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