MYSM1 Rabbit pAb
Cat#:DPA05015应用:WB,IP
| Product Name: | MYSM1 Rabbit pAb |
| Cat No.: | DPA05015 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IP |
| Recommended Dilution: | WB: 1:1000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human MYSM1 |
| Calculated Molecular Weight: | 95 kDa |
| Observed Molecular Weight: | 96,55 kDa |
| GenBank Accession Number: | Q5VVJ2 |
| Gene ID (NCBI): | 114803 |
| Synonyms: | 2ADUB; 2A-DUB |
| Background: | Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. |
| Category: | Primary Ab |