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EAAT2 Rabbit pAb

Cat No.: DPA05033
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Product Name: EAAT2 Rabbit pAb
Cat No.: DPA05033
Clonality: Polyclonal
Species Reactivity: Mouse, Rat
Tested Applications: WB,IHC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:200
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of mouse EAAT2
Calculated Molecular Weight: 62 kDa
Observed Molecular Weight: 65 kDa
GenBank Accession Number: P43006
Gene ID (NCBI): 20511
Synonyms: GLT1; Eaat2; GLT-1; MGLT1; AI159670; 1700091C19Rik; 2900019G14Rik
Background: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7698742, PubMed:7557442, PubMed:9373176). Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport (By similarity). Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (PubMed:9180080).
Category: Primary Ab
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