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TIMP1 Rabbit pAb

Cat No.: DPA05058
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Product Name: TIMP1 Rabbit pAb
Cat No.: DPA05058
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF
Recommended Dilution: WB: 1:1000
IHC: 1:200
ICC/IF: 1:100
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human TIMP1
Calculated Molecular Weight: 23 kDa
Observed Molecular Weight: 26 kDa
GenBank Accession Number: P01033
Gene ID (NCBI): 7076
Synonyms: EPA; EPO; HCI; CLGI; TIMP; TIMP-1
Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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