Recombinant Human THPO Protein
Cat#:TP04208应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Thrombopoietin Rabbit pAb |
| Cat No.: | DPA05094 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:500 ICC/IF: 1:20 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Thrombopoietin |
| Calculated Molecular Weight: | 38 kDa |
| Observed Molecular Weight: | 38 kDa |
| GenBank Accession Number: | P40225 |
| Gene ID (NCBI): | 7066 |
| Synonyms: | ML; TPO; MGDF; MKCSF; MPLLG; THCYT1 |
| Background: | Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014] |
| Category: | Primary Ab |