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分子生物学
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查看说明书Recombinant Mouse CNOT7 Protein
Cat#:TP01664应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | CNOT7 Rabbit pAb |
| Cat No.: | DPA05176 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:200 FC: 1:100 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of mouse CNOT7 |
| Calculated Molecular Weight: | 33 kDa |
| Observed Molecular Weight: | 33 kDa |
| GenBank Accession Number: | Q60809 |
| Gene ID (NCBI): | 18983 |
| Synonyms: | Caf1; Pop2; CAF-1; AU022737 |
| Background: | Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for miRNA-mediated mRNA deadenylation. |
| Category: | Primary Ab |
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