蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Mre11 Rabbit pAb
Cat#:DPA02916应用：WB,IHC,FC
| Product Name: | Mre11 Rabbit pAb |
| Cat No.: | DPA05193 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Mre11 |
| Calculated Molecular Weight: | 81 kDa |
| Observed Molecular Weight: | 81 kDa |
| GenBank Accession Number: | P49959 |
| Gene ID (NCBI): | 4361 |
| Synonyms: | ATLD; HNGS1; MRE11A; MRE11B |
| Background: | This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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