Recombinant B-Cell CLL/Lymphoma 6 (Bcl6)
Cat#:TP06399应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Bcl6 Rabbit pAb |
| Cat No.: | DPA05205 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Bcl6 |
| Calculated Molecular Weight: | 78 kDa |
| Observed Molecular Weight: | 85 kDa |
| GenBank Accession Number: | P41182 |
| Gene ID (NCBI): | 604 |
| Synonyms: | BCL5; LAZ3; BCL6A; ZNF51; ZBTB27 |
| Background: | The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| Category: | Primary Ab |