TFE3 Rabbit pAb
Cat#:DPA05234应用:IHC,ICC/IF,FC
Product Name: | TFE3 Recombinant Rabbit mAb |
Cat No.: | RMA01013 |
Clonality: | Monoclonal |
Species Reactivity: | Human |
Tested Applications: | IHC,ICC/IF,FC |
Recommended Dilution: | IHC,ICC/IF,FC |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human TFE3 |
Calculated Molecular Weight: | 62 kDa |
GenBank Accession Number: | P19532 |
Gene ID (NCBI): | 7030 |
Synonyms: | TFEA; RCCP2; RCCX1; bHLHe33 |
Background: | This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
Category: | Primary Ab |