eIF3B Rabbit pAb
Cat#:DPA04676应用:WB,ICC/IF,FC,IP
| Product Name: | eIF3B Recombinant Rabbit mAb |
| Cat No.: | RMA01226 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB,IHC |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human eIF3B |
| Calculated Molecular Weight: | 93 kDa |
| Observed Molecular Weight: | 117 kDa |
| GenBank Accession Number: | P55884 |
| Gene ID (NCBI): | 8662 |
| Synonyms: | PRT1; EIF3S9; EIF3-ETA; EIF3-P110; EIF3-P116 |
| Background: | RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. |
| Category: | Primary Ab |