蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书RASGRF1 Rabbit pAb
Cat#:DPA04346应用：WB
| Product Name: | RASGRF1 Recombinant Rabbit mAb |
| Cat No.: | RMA01349 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human RASGRF1 |
| Calculated Molecular Weight: | 145 kDa |
| Observed Molecular Weight: | 145 kDa |
| GenBank Accession Number: | Q13972 |
| Gene ID (NCBI): | 5923 |
| Synonyms: | GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1 |
| Background: | The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009] |
| Category: | Primary Ab |
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