Recombinant Human CFD Protein
Cat#:TP01591应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Factor D Recombinant Rabbit mAb |
| Cat No.: | RMA01397 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Factor D |
| Calculated Molecular Weight: | 27 kDa |
| Observed Molecular Weight: | 27 kDa |
| GenBank Accession Number: | P00746 |
| Gene ID (NCBI): | 1675 |
| Synonyms: | DF; ADN; PFD; ADIPSIN |
| Background: | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015] |
| Category: | Primary Ab |