XPD Rabbit pAb
Cat#:DPA03315应用:WB,IHC,ICC/IF
| Product Name: | XPD Recombinant Rabbit mAb |
| Cat No.: | RMA01741 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF |
| Recommended Dilution: | WB,IHC,ICC/IF |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human XPD |
| Calculated Molecular Weight: | 87 kDa |
| Observed Molecular Weight: | 80 kDa |
| GenBank Accession Number: | P18074 |
| Gene ID (NCBI): | 2068 |
| Synonyms: | EM9; TTD; XPD; TTD1; COFS2; TFIIH |
| Background: | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
| Category: | Primary Ab |