DPD Rabbit pAb
Cat#:DPA02961应用:WB,IHC,ICC/IF
| Product Name: | DPD Recombinant Rabbit mAb |
| Cat No.: | RMA01886 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF |
| Recommended Dilution: | WB,IHC,ICC/IF |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human DPD |
| Calculated Molecular Weight: | 111 kDa |
| Observed Molecular Weight: | 111 kDa |
| GenBank Accession Number: | Q12882 |
| Gene ID (NCBI): | 1806 |
| Synonyms: | DHP; DPD; DHPDHASE |
| Background: | The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
| Category: | Primary Ab |