蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书NXF1 Rabbit pAb
Cat#:DPA02622应用：WB,IHC,ICC/IF,IP
| Product Name: | NXF1 Recombinant Rabbit mAb |
| Cat No.: | RMA02041 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,IP |
| Recommended Dilution: | WB,IHC,ICC/IF,IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human NXF1 |
| Calculated Molecular Weight: | 70 kDa |
| Observed Molecular Weight: | 70 kDa |
| GenBank Accession Number: | Q9UBU9 |
| Gene ID (NCBI): | 10482 |
| Synonyms: | TAP; MEX67 |
| Background: | This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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