蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书SF3B1 Rabbit pAb
Cat#:DPA02452应用：WB,IHC,ICC/IF,FC
| Product Name: | SF3B1 Recombinant Rabbit mAb |
| Cat No.: | RMA02132 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB,IHC,ICC/IF,FC |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human SF3B1 |
| Calculated Molecular Weight: | 146 kDa |
| Observed Molecular Weight: | 155 kDa |
| GenBank Accession Number: | O75533 |
| Gene ID (NCBI): | 23451 |
| Synonyms: | MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155 |
| Background: | This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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