Recombinant Ataxin 3 (ATXN3)
Cat#:TP01258应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Ataxin 3 Recombinant Rabbit mAb |
| Cat No.: | RMA02401 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Ataxin 3 |
| Calculated Molecular Weight: | 42 kDa |
| Observed Molecular Weight: | 42 kDa |
| GenBank Accession Number: | P54252 |
| Gene ID (NCBI): | 4287 |
| Synonyms: | AT3; JOS; MJD; ATX3; MJD1; SCA3 |
| Background: | Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016] |
| Category: | Primary Ab |