Recombinant Interleukin 4 (IL4)
Cat#:TP02600应用:Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | IL-4 Recombinant Rabbit mAb |
| Cat No.: | RMA02904 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB, ICC/IF, FC |
| Recommended Dilution: | WB, ICC/IF, FC |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human IL4 |
| Calculated Molecular Weight: | 17 kDa |
| Observed Molecular Weight: | 17 kDa |
| GenBank Accession Number: | P05112 |
| Gene ID (NCBI): | 3565 |
| Synonyms: | BSF1; IL-4; BCGF1; BSF-1; BCGF-1 |
| Background: | The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |