Alpha-synuclein Rabbit pAb
Cat#:DPA03936应用:WB,IHC,IP
| Product Name: | Phospho-Alpha-synuclein (Tyr125) Rabbit pAb |
| Cat No.: | DPA05390 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr125 of human Alpha-synuclein |
| Calculated Molecular Weight: | 14 kDa |
| Observed Molecular Weight: | 16 kDa |
| GenBank Accession Number: | P37840 |
| Gene ID (NCBI): | 6622 |
| Synonyms: | PD1; NACP; PARK1; PARK4 |
| Background: | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016] |
| Category: | Primary Ab |